Cell based SARS-CoV-2 Pseudovirus neutralization Assays (Blocking Entry)

  • Drugs or antibodies to block virus entry – for therapy and prevention
  • Vaccine validation
  • Cell Based
  • Equipment: HCS imaging platform or Reader

Product Introduction

  1. Luciferase or GFP expressing pseudotyped SARS-CoV-2 virus were generated in cells.
  2. Pseudoviruses were harvested and incubated with the neutralizing antibody or drugs.
  3. Mixture of Pseudoviruses were added into cells.
  4. The pseudovirus neutralization inhibition rate of the antibody or inhibition rate of drug can be calculated by the luciferase luminescence value or GFP expression effiency.

Equipment: HCS imaging platform or Reader

*Customized platform with different cell lines is available